Upgrade work is taking place between Milton Keynes and Rugby on the West Coast mainline to help protect against the risk of flooding.
The major work will take place between the 4th and 12 January.
The work will boost reliability on the economically important route by preventing rain from flooding the tracks.
Trains will be diverted via Northampton to bypass the 4km long drainage work whilst the upgrades take place.
Fewer London Northwestern Railway (LNR) services will run between Crewe and Euston with passengers needing to change at Rugby.
James Dean, Network Rail’s West Coast South Route Director spoke on the improvement work taking place.
Mr Dean said: “This major work on the West Coast main line is vital to protect it from the risk of future flooding.
“We always try to do our work with the least disruption to passengers as possible.
“During this project we can keep people on the move by using a diversionary route.
“However, there will be fewer services, longer journey times and some passengers may need to change trains.
“I’d urge people to please check National Rail Enquiries before they travel.”
Lawrence Bowman, Customer Experience Director for LNR commented on the potential disruption caused by the work.
Mr Bowman said: “This… will improve the reliability of our rail infrastructure and reduce the likelihood of delays in the future.
“I urge customers to plan their rail travel in advance during the West Coast Main Line work near Milton Keynes in January.”